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Systems biology modeling of omics data: effect of cyclosporine a on the Nrf2 pathway in human renal cells

BACKGROUND: Incorporation of omic data streams for building improved systems biology models has great potential for improving their predictions of biological outcomes. We have recently shown that cyclosporine A (CsA) strongly activates the nuclear factor (erythroid-derived 2)-like 2 pathway (Nrf2) i...

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Detalles Bibliográficos
Autores principales: Hamon, Jérémy, Jennings, Paul, Bois, Frederic Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089556/
https://www.ncbi.nlm.nih.gov/pubmed/24964791
http://dx.doi.org/10.1186/1752-0509-8-76