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A phosphate-centric paradigm for pathophysiology and therapy of chronic kidney disease

Extracellular phosphate is toxic to the cell at high concentrations. When the phosphate level is increased in the blood by impaired urinary phosphate excretion, premature aging ensues. When the phosphate level is increased in the urine by dietary phosphate overload, this may lead to kidney damage (t...

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Detalles Bibliográficos
Autor principal: Kuro-o, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089674/
https://www.ncbi.nlm.nih.gov/pubmed/25019024
http://dx.doi.org/10.1038/kisup.2013.88