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A phosphate-centric paradigm for pathophysiology and therapy of chronic kidney disease
Extracellular phosphate is toxic to the cell at high concentrations. When the phosphate level is increased in the blood by impaired urinary phosphate excretion, premature aging ensues. When the phosphate level is increased in the urine by dietary phosphate overload, this may lead to kidney damage (t...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089674/ https://www.ncbi.nlm.nih.gov/pubmed/25019024 http://dx.doi.org/10.1038/kisup.2013.88 |