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Oxidative Stress in Mouse Sperm Impairs Embryo Development, Fetal Growth and Alters Adiposity and Glucose Regulation in Female Offspring

Paternal health cues are able to program the health of the next generation however the mechanism for this transmission is unknown. Reactive oxygen species (ROS) are increased in many paternal pathologies, some of which program offspring health, and are known to induce DNA damage and alter the methyl...

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Detalles Bibliográficos
Autores principales: Lane, Michelle, McPherson, Nicole O., Fullston, Tod, Spillane, Marni, Sandeman, Lauren, Kang, Wan Xian, Zander-Fox, Deirdre L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089912/
https://www.ncbi.nlm.nih.gov/pubmed/25006800
http://dx.doi.org/10.1371/journal.pone.0100832