Cruentaren A Binds F(1)F(0) ATP Synthase To Modulate the Hsp90 Protein Folding Machinery

[Image: see text] The molecular chaperone Hsp90 requires the assistance of immunophilins, co-chaperones, and partner proteins for the conformational maturation of client proteins. Hsp90 inhibition represents a promising anticancer strategy due to the dependence of numerous oncogenic signaling pathwa...

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Detalles Bibliográficos
Autores principales: Hall, Jessica A., Kusuma, Bhaskar Reddy, Brandt, Gary E. L., Blagg, Brian S. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090037/
https://www.ncbi.nlm.nih.gov/pubmed/24450340
http://dx.doi.org/10.1021/cb400906e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090037/
https://www.ncbi.nlm.nih.gov/pubmed/24450340
http://dx.doi.org/10.1021/cb400906e

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