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Cruentaren A Binds F(1)F(0) ATP Synthase To Modulate the Hsp90 Protein Folding Machinery

[Image: see text] The molecular chaperone Hsp90 requires the assistance of immunophilins, co-chaperones, and partner proteins for the conformational maturation of client proteins. Hsp90 inhibition represents a promising anticancer strategy due to the dependence of numerous oncogenic signaling pathwa...

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Detalles Bibliográficos
Autores principales:	Hall, Jessica A., Kusuma, Bhaskar Reddy, Brandt, Gary E. L., Blagg, Brian S. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090037/ https://www.ncbi.nlm.nih.gov/pubmed/24450340 http://dx.doi.org/10.1021/cb400906e

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