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CD127 Expression, Exhaustion Status and Antigen Specific Proliferation Predict Sustained Virologic Response to IFN in HCV/HIV Co-Infected Individuals

Hepatitis C virus (HCV) infection is a major cause of morbidity and mortality in the HIV co-infected population. Interferon-alpha (IFN-α) remains a major component of anti-HCV therapy despite its deleterious effects on the immune system. Furthermore, IFN-α was recently shown to diminish the size of...

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Detalles Bibliográficos
Autores principales: Kared, Hassen, Saeed, Sahar, Klein, Marina B., Shoukry, Naglaa H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090061/
https://www.ncbi.nlm.nih.gov/pubmed/25007250
http://dx.doi.org/10.1371/journal.pone.0101441