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Combined NADPH Oxidase 1 and Interleukin 10 Deficiency Induces Chronic Endoplasmic Reticulum Stress and Causes Ulcerative Colitis-Like Disease in Mice

Ulcerative colitis (UC) is a chronic inflammatory bowel disease affecting the rectum which progressively extents. Its etiology remains unknown and the number of treatments available is limited. Studies of UC patients have identified an unbalanced endoplasmic reticulum (ER) stress in the non-inflamed...

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Detalles Bibliográficos
Autores principales: Tréton, Xavier, Pedruzzi, Eric, Guichard, Cécile, Ladeiro, Yannick, Sedghi, Shirin, Vallée, Mélissa, Fernandez, Neike, Bruyère, Emilie, Woerther, Paul-Louis, Ducroc, Robert, Montcuquet, Nicolas, Freund, Jean-Noel, Van Seuningen, Isabelle, Barreau, Frédérick, Marah, Assiya, Hugot, Jean-Pierre, Cazals-Hatem, Dominique, Bouhnik, Yoram, Daniel, Fanny, Ogier-Denis, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090121/
https://www.ncbi.nlm.nih.gov/pubmed/25014110
http://dx.doi.org/10.1371/journal.pone.0101669