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Combined NADPH Oxidase 1 and Interleukin 10 Deficiency Induces Chronic Endoplasmic Reticulum Stress and Causes Ulcerative Colitis-Like Disease in Mice
Ulcerative colitis (UC) is a chronic inflammatory bowel disease affecting the rectum which progressively extents. Its etiology remains unknown and the number of treatments available is limited. Studies of UC patients have identified an unbalanced endoplasmic reticulum (ER) stress in the non-inflamed...
Autores principales: | Tréton, Xavier, Pedruzzi, Eric, Guichard, Cécile, Ladeiro, Yannick, Sedghi, Shirin, Vallée, Mélissa, Fernandez, Neike, Bruyère, Emilie, Woerther, Paul-Louis, Ducroc, Robert, Montcuquet, Nicolas, Freund, Jean-Noel, Van Seuningen, Isabelle, Barreau, Frédérick, Marah, Assiya, Hugot, Jean-Pierre, Cazals-Hatem, Dominique, Bouhnik, Yoram, Daniel, Fanny, Ogier-Denis, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090121/ https://www.ncbi.nlm.nih.gov/pubmed/25014110 http://dx.doi.org/10.1371/journal.pone.0101669 |
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