The Capacity of Red Blood Cells to Reduce Nitrite Determines Nitric Oxide Generation under Hypoxic Conditions

Nitric oxide (NO) is a key regulator of vascular tone. Endothelial nitric oxide synthase (eNOS) is responsible for NO generation under normoxic conditions. Under hypoxia however, eNOS is inactive and red blood cells (RBC) provide an alternative NO generation pathway from nitrite to regulate hypoxic...

Descripción completa

Detalles Bibliográficos
Autores principales: Fens, Marcel H., Larkin, Sandra K., Oronsky, Bryan, Scicinski, Jan, Morris, Claudia R., Kuypers, Frans A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090171/
https://www.ncbi.nlm.nih.gov/pubmed/25007272
http://dx.doi.org/10.1371/journal.pone.0101626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090171/
https://www.ncbi.nlm.nih.gov/pubmed/25007272
http://dx.doi.org/10.1371/journal.pone.0101626

Ejemplares similares