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Large Scale Analysis of Phenotype-Pathway Relationships Based on GWAS Results

The widely used pathway-based approach for interpreting Genome Wide Association Studies (GWAS), assumes that since function is executed through the interactions of multiple genes, different perturbations of the same pathway would result in a similar phenotype. This assumption, however, was not syste...

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Detalles Bibliográficos
Autores principales: Brodie, Aharon, Tovia-Brodie, Oholi, Ofran, Yanay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090199/
https://www.ncbi.nlm.nih.gov/pubmed/25007247
http://dx.doi.org/10.1371/journal.pone.0100887