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Large Scale Analysis of Phenotype-Pathway Relationships Based on GWAS Results
The widely used pathway-based approach for interpreting Genome Wide Association Studies (GWAS), assumes that since function is executed through the interactions of multiple genes, different perturbations of the same pathway would result in a similar phenotype. This assumption, however, was not syste...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090199/ https://www.ncbi.nlm.nih.gov/pubmed/25007247 http://dx.doi.org/10.1371/journal.pone.0100887 |