Inhibitor of Apoptosis Proteins (IAPs) as therapeutic targets in Multiple Myeloma (MM)

The inhibitor of apoptosis (IAP) proteins plays a critical role in the control of apoptotic machinery, and has been explored as a therapeutic target. Here, we have examined the functional importance of IAPs in multiple myeloma (MM) by using a Smac-mimetic LCL161. We observed that LCL161 was able to...

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Detalles Bibliográficos
Autores principales: Ramakrishnan, Vijay, Painuly, Utkarsh, Kimlinger, Teresa, Haug, Jessica, Rajkumar, S. Vincent, Kumar, Shaji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090267/
https://www.ncbi.nlm.nih.gov/pubmed/24402161
http://dx.doi.org/10.1038/leu.2014.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090267/
https://www.ncbi.nlm.nih.gov/pubmed/24402161
http://dx.doi.org/10.1038/leu.2014.2

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