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Heat treatment of retinal pigment epithelium induces production of elastic lamina components and antiangiogenic activity

Age-related macular degeneration (AMD) is the leading cause of blindness in the Western world. In advanced AMD, new vessels from choriocapillaris (CC) invade through the Bruch's membrane (BrM) into the retina, forming choroidal neovascularization (CNV). BrM, an elastic lamina that is located be...

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Detalles Bibliográficos
Autores principales: Sekiyama, Eiichi, Saint-Geniez, Magali, Yoneda, Kazuhito, Hisatomi, Toshio, Nakao, Shintaro, Walshe, Tony E., Maruyama, Kazuichi, Hafezi-Moghadam, Ali, Miller, Joan W., Kinoshita, Shigeru, D'Amore, Patricia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090388/
https://www.ncbi.nlm.nih.gov/pubmed/22067481
http://dx.doi.org/10.1096/fj.11-184127