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Little evidence for association between the TGFBR1*6A variant and colorectal cancer: a family-based association study on non-syndromic family members from Australia and Spain

BACKGROUND: Genome-wide linkage studies have identified the 9q22 chromosomal region as linked with colorectal cancer (CRC) predisposition. A candidate gene in this region is transforming growth factor β receptor 1 (TGFBR1). Investigation of TGFBR1 has focused on the common genetic variant rs11466445...

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Detalles Bibliográficos
Autores principales: Ross, Jason P, Lockett, Linda J, Tabor, Bruce, Saunders, Ian W, Young, Graeme P, Macrae, Finlay, Blanco, Ignacio, Capella, Gabriel, Brown, Glenn S, Lockett, Trevor J, Hannan, Garry N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090415/
https://www.ncbi.nlm.nih.gov/pubmed/24981199
http://dx.doi.org/10.1186/1471-2407-14-475