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NTPDase5/PCPH as a New Target in Highly Aggressive Tumors: A Systematic Review

The protooncogene PCPH was recently identified as being the ectonucleoside triphosphate diphosphohydrolase 5 (ENTPD5). This protooncogene is converted into an oncogene by a single base pair deletion, resulting in frame change and producing a premature stop codon, leading to a mutated protein (mt-PCP...

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Detalles Bibliográficos
Autores principales: Bracco, Paula Andreghetto, Bertoni, Ana Paula Santin, Wink, Márcia Rosângela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090452/
https://www.ncbi.nlm.nih.gov/pubmed/25045656
http://dx.doi.org/10.1155/2014/123010