Enhanced Analgesic Properties and Reduced Ulcerogenic Effect of a Mononuclear Copper(II) Complex with Fenoprofen in Comparison to the Parent Drug: Promising Insights in the Treatment of Chronic Inflammatory Diseases

Analgesic and ulcerogenic properties have been studied for the copper(II) coordination complex of the nonsteroidal anti-inflammatory drug Fenoprofen and imidazole [Cu(fen)(2)(im)(2)] (Cu: copper(II) ion; fen: fenoprofenate anion from Fenoprofen, im: imidazole). A therapeutic dose of 28 mg/kg was tes...

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Detalles Bibliográficos
Autores principales: Agotegaray, Mariela, Gumilar, Fernanda, Boeris, Mónica, Toso, Ricardo, Minetti, Alejandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090501/
https://www.ncbi.nlm.nih.gov/pubmed/25050353
http://dx.doi.org/10.1155/2014/505987

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090501/
https://www.ncbi.nlm.nih.gov/pubmed/25050353
http://dx.doi.org/10.1155/2014/505987

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