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Recent methods for measuring dopamine D3 receptor occupancy in vivo: importance for drug development

There is considerable interest in developing highly selective dopamine (DA) D3 receptor ligands for a variety of mental health disorders. DA D3 receptors have been implicated in Parkinson’s disease, schizophrenia, anxiety, depression, and substance use disorders. The most concrete evidence suggests...

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Detalles Bibliográficos
Autores principales: Le Foll, Bernard, Wilson, Alan A., Graff, Ariel, Boileau, Isabelle, Di Ciano, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090596/
https://www.ncbi.nlm.nih.gov/pubmed/25071579
http://dx.doi.org/10.3389/fphar.2014.00161