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Visualizing active membrane protein complexes by electron cryotomography

Unravelling the structural organization of membrane protein machines in their active state and native lipid environment is a major challenge in modern cell biology research. Here we develop the STAMP (Specifically TArgeted Membrane nanoParticle) technique as a strategy to localize protein complexes...

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Detalles Bibliográficos
Autores principales: Gold, Vicki A.M., Ieva, Raffaele, Walter, Andreas, Pfanner, Nikolaus, van der Laan, Martin, Kühlbrandt, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090714/
https://www.ncbi.nlm.nih.gov/pubmed/24942077
http://dx.doi.org/10.1038/ncomms5129