An RNA-seq method for defining endoribonuclease cleavage specificity identifies dual rRNA substrates for toxin MazF-mt3

Toxin-antitoxin (TA) systems are widespread in prokaryotes. Among these, the mazEF TA system encodes an endoribonucleolytic toxin, MazF, that inhibits growth by sequence-specific cleavage of single-stranded RNA. Defining the physiological targets of a MazF toxin first requires the identification of...

Descripción completa

Detalles Bibliográficos
Autores principales: Schifano, Jason M., Vvedenskaya, Irina O., Knoblauch, Jared G., Ouyang, Ming, Nickels, Bryce E., Woychik, Nancy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090939/
https://www.ncbi.nlm.nih.gov/pubmed/24709835
http://dx.doi.org/10.1038/ncomms4538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090939/
https://www.ncbi.nlm.nih.gov/pubmed/24709835
http://dx.doi.org/10.1038/ncomms4538

Ejemplares similares