Cargando…
An RNA-seq method for defining endoribonuclease cleavage specificity identifies dual rRNA substrates for toxin MazF-mt3
Toxin-antitoxin (TA) systems are widespread in prokaryotes. Among these, the mazEF TA system encodes an endoribonucleolytic toxin, MazF, that inhibits growth by sequence-specific cleavage of single-stranded RNA. Defining the physiological targets of a MazF toxin first requires the identification of...
Autores principales: | Schifano, Jason M., Vvedenskaya, Irina O., Knoblauch, Jared G., Ouyang, Ming, Nickels, Bryce E., Woychik, Nancy A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090939/ https://www.ncbi.nlm.nih.gov/pubmed/24709835 http://dx.doi.org/10.1038/ncomms4538 |
Ejemplares similares
-
tRNA is a new target for cleavage by a MazF toxin
por: Schifano, Jason M., et al.
Publicado: (2016) -
AAU-Specific RNA Cleavage Mediated by MazF Toxin Endoribonuclease Conserved in Nitrosomonas europaea
por: Miyamoto, Tatsuki, et al.
Publicado: (2016) -
Characterization of a Deinococcus radiodurans MazF: A UACA‐specific RNA endoribonuclease
por: Miyamoto, Tatsuki, et al.
Publicado: (2017) -
Insights into the global effect on Staphylococcus aureus growth arrest by induction of the endoribonuclease MazF toxin
por: Sierra, Roberto, et al.
Publicado: (2020) -
The Sole Mycobacterium smegmatis MazF Toxin Targets tRNA(Lys) to Impart Highly Selective, Codon-Dependent Proteome Reprogramming
por: Barth, Valdir Cristovao, et al.
Publicado: (2020)