Expression and detection of LINE-1 ORF-encoded proteins

LINE-1 (L1) elements are endogenous retrotransposons active in mammalian genomes. The L1 RNA is bicistronic, encoding two non-overlapping open reading frames, ORF1 and ORF2, whose protein products (ORF1p and ORF2p) bind the L1 RNA to form a ribonucleoprotein (RNP) complex that is presumed to be a cr...

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Detalles Bibliográficos
Autores principales: Dai, Lixin, LaCava, John, Taylor, Martin S, Boeke, Jef D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091050/
https://www.ncbi.nlm.nih.gov/pubmed/25054082
http://dx.doi.org/10.4161/mge.29319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091050/
https://www.ncbi.nlm.nih.gov/pubmed/25054082
http://dx.doi.org/10.4161/mge.29319

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