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Radiation-induced survival responses promote immunogenic modulation to enhance immunotherapy in combinatorial regimens
Tumor cells that survive radiation are more sensitive to T-cell-mediated lysis due to a spectrum of biological adaptations to cellular stress (defined as immunogenic modulation), including enhanced antigen processing and cell-surface presence of calreticulin. This mechanism can be exploited to maxim...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091054/ https://www.ncbi.nlm.nih.gov/pubmed/25097803 http://dx.doi.org/10.4161/onci.28643 |