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G-protein-coupled receptor signaling and polarized actin dynamics drive cell-in-cell invasion

Homotypic or entotic cell-in-cell invasion is an integrin-independent process observed in carcinoma cells exposed during conditions of low adhesion such as in exudates of malignant disease. Although active cell-in-cell invasion depends on RhoA and actin, the precise mechanism as well as the underlyi...

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Detalles Bibliográficos
Autores principales: Purvanov, Vladimir, Holst, Manuel, Khan, Jameel, Baarlink, Christian, Grosse, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091095/
https://www.ncbi.nlm.nih.gov/pubmed/24950964
http://dx.doi.org/10.7554/eLife.02786