Setting an Upper Limit on the Myoglobin Iron(IV)Hydroxide pK(a): Insight into Axial Ligand Tuning in Heme Protein Catalysis

[Image: see text] To provide insight into the iron(IV)hydroxide pK(a) of histidine ligated heme proteins, we have probed the active site of myoglobin compound II over the pH range of 3.9–9.5, using EXAFS, Mössbauer, and resonance Raman spectroscopies. We find no indication of ferryl protonation over...

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Detalles Bibliográficos
Autores principales: Yosca, Timothy H., Behan, Rachel K., Krest, Courtney M., Onderko, Elizabeth L., Langston, Matthew C., Green, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091272/
https://www.ncbi.nlm.nih.gov/pubmed/24875119
http://dx.doi.org/10.1021/ja503588n

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091272/
https://www.ncbi.nlm.nih.gov/pubmed/24875119
http://dx.doi.org/10.1021/ja503588n

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