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Enantioselective Nucleophile-Catalyzed Synthesis of Tertiary Alkyl Fluorides via the α-Fluorination of Ketenes: Synthetic and Mechanistic Studies

[Image: see text] The catalytic asymmetric synthesis of alkyl fluorides, particularly α-fluorocarbonyl compounds, has been the focus of substantial effort in recent years. While significant progress has been described in the formation of enantioenriched secondary alkyl fluorides, advances in the gen...

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Detalles Bibliográficos
Autores principales: Lee, Sarah Yunmi, Neufeind, Stefan, Fu, Gregory C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091276/
https://www.ncbi.nlm.nih.gov/pubmed/24922581
http://dx.doi.org/10.1021/ja5044209