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ABC transporters in CSCs membranes as a novel target for treating tumor relapse

CSCs are responsible for the high rate of recurrence and chemoresistance of different types of cancer. The current antineoplastic agents able to inhibit bulk replicating cancer cells and radiation treatment are not efficacious toward CSCs since this subpopulation has several intrinsic mechanisms of...

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Detalles Bibliográficos
Autores principales: Zinzi, Laura, Contino, Marialessandra, Cantore, Mariangela, Capparelli, Elena, Leopoldo, Marcello, Colabufo, Nicola A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091306/
https://www.ncbi.nlm.nih.gov/pubmed/25071581
http://dx.doi.org/10.3389/fphar.2014.00163