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Gene Expression Regulation by Agonist-Independent Constitutive Signaling of Melanocortin-1 Receptor

BACKGROUND: Melanocortin-1 receptor (Mc1r), a key signaling receptor for melanogenesis, has been reported to mediate migration of B16F10 melanoma cells. Interestingly, this activity appears to be a part of the constitutive signaling of Mc1r. METHODS: We carried out small interfering RNA-mediated kno...

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Detalles Bibliográficos
Autores principales: Seong, Ikjoo, Kim, Jaesang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Endocrine Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091487/
https://www.ncbi.nlm.nih.gov/pubmed/25031891
http://dx.doi.org/10.3803/EnM.2014.29.2.179