SETX sumoylation: A link between DNA damage and RNA surveillance disrupted in AOA2

Senataxin (SETX) is a putative RNA:DNA helicase that is mutated in two distinct juvenile neurological disorders, AOA2 and ALS4. SETX is involved in the response to oxidative stress and is suggested to resolve R loops formed at transcription termination sites or at sites of collisions between the tra...

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Detalles Bibliográficos
Autores principales: Richard, Patricia, Manley, James L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Addendum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091563/
https://www.ncbi.nlm.nih.gov/pubmed/25054092
http://dx.doi.org/10.4161/rdis.27744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091563/
https://www.ncbi.nlm.nih.gov/pubmed/25054092
http://dx.doi.org/10.4161/rdis.27744

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