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Increased Neutrophil Extracellular Trap–Mediated Staphylococcus aureus Clearance Through Inhibition of Nuclease Activity by Clindamycin and Immunoglobulin

The Gram-positive human pathogen Staphylococcus aureus causes a variety of human diseases such as skin infections, pneumonia, and endocarditis. The micrococcal nuclease Nuc1 is one of the major S. aureus virulence factors and allows the bacterium to avoid neutrophil extracellular trap (NET)–mediated...

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Detalles Bibliográficos
Autores principales: Schilcher, Katrin, Andreoni, Federica, Uchiyama, Satoshi, Ogawa, Taiji, Schuepbach, Reto A., Zinkernagel, Annelies S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091580/
https://www.ncbi.nlm.nih.gov/pubmed/24526740
http://dx.doi.org/10.1093/infdis/jiu091