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Increased Neutrophil Extracellular Trap–Mediated Staphylococcus aureus Clearance Through Inhibition of Nuclease Activity by Clindamycin and Immunoglobulin
The Gram-positive human pathogen Staphylococcus aureus causes a variety of human diseases such as skin infections, pneumonia, and endocarditis. The micrococcal nuclease Nuc1 is one of the major S. aureus virulence factors and allows the bacterium to avoid neutrophil extracellular trap (NET)–mediated...
Autores principales: | Schilcher, Katrin, Andreoni, Federica, Uchiyama, Satoshi, Ogawa, Taiji, Schuepbach, Reto A., Zinkernagel, Annelies S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091580/ https://www.ncbi.nlm.nih.gov/pubmed/24526740 http://dx.doi.org/10.1093/infdis/jiu091 |
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