An Investigational Antiviral Drug, DAS181, Effectively Inhibits Replication of Zoonotic Influenza A Virus Subtype H7N9 and Protects Mice From Lethality

Human infections caused by avian influenza A virus type subtype H7N9 have been associated with substantial morbidity and mortality. Emergence of virus variants carrying markers of decreased susceptibility to neuraminidase inhibitors was reported. Here we show that DAS181 (Fludase), an antiviral drug...

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Detalles Bibliográficos
Autores principales: Marjuki, Henju, Mishin, Vasiliy P., Chesnokov, Anton P., De La Cruz, Juan A., Fry, Alicia M., Villanueva, Julie, Gubareva, Larisa V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091581/
https://www.ncbi.nlm.nih.gov/pubmed/24569063
http://dx.doi.org/10.1093/infdis/jiu105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091581/
https://www.ncbi.nlm.nih.gov/pubmed/24569063
http://dx.doi.org/10.1093/infdis/jiu105

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