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Ménage à trois: Sustained therapeutic anti-tumor immunity requires multiple partners in malignant glioma

Glioblastoma is an aggressive primary brain cancer. Given our interest in novel immunotherapies, we have recently shown that inhibiting CTLA-4, PD-L1 and IDO results in a dramatic survival advantage in mice with brain tumors. Our preclinical study supports the rapid translation of this approach into...

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Detalles Bibliográficos
Autores principales: Wainwright, Derek A, Lesniak, Maciej S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091585/
https://www.ncbi.nlm.nih.gov/pubmed/25057450
http://dx.doi.org/10.4161/onci.28927