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Role of cancer stem cell-associated inflammation in creating pro-inflammatory tumorigenic microenvironments

We identify novel mechanisms whereby chemoresistance enables cancer stem cells to create pro-inflammatory tumor microenvironments. Chemoresistant cancer stem cells promote M2 macrophage differentiation through interferon-regulatory factor-5 (IRF5)- and macrophage-colony stimulating factor (M-CSF)-de...

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Detalles Bibliográficos
Autor principal: Jinushi, Masahisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091611/
https://www.ncbi.nlm.nih.gov/pubmed/25057449
http://dx.doi.org/10.4161/onci.28862