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The anti-inflammatory role of tissue inhibitor of metalloproteinase-2 in lipopolysaccharide-stimulated microglia

BACKGROUND: Tissue inhibitors of metalloproteinases (TIMPs) are known to be endogenous inhibitors of matrix metalloproteinases (MMPs). Our preliminary study showed that TIMP-2 is constitutively expressed in microglia but significantly inhibited by lipopolysaccharide (LPS) treatment. The current stud...

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Detalles Bibliográficos
Autores principales: Lee, Eun-Jung, Kim, Hee-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091675/
https://www.ncbi.nlm.nih.gov/pubmed/24970341
http://dx.doi.org/10.1186/1742-2094-11-116