Unraveling Genetic Modifiers in the Gria4 Mouse Model of Absence Epilepsy

Absence epilepsy (AE) is a common type of genetic generalized epilepsy (GGE), particularly in children. AE and GGE are complex genetic diseases with few causal variants identified to date. Gria4 deficient mice provide a model of AE, one for which the common laboratory inbred strain C3H/HeJ (HeJ) har...

Descripción completa

Detalles Bibliográficos
Autores principales: Frankel, Wayne N., Mahaffey, Connie L., McGarr, Tracy C., Beyer, Barbara J., Letts, Verity A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091709/
https://www.ncbi.nlm.nih.gov/pubmed/25010494
http://dx.doi.org/10.1371/journal.pgen.1004454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091709/
https://www.ncbi.nlm.nih.gov/pubmed/25010494
http://dx.doi.org/10.1371/journal.pgen.1004454

Ejemplares similares