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Unraveling Genetic Modifiers in the Gria4 Mouse Model of Absence Epilepsy

Absence epilepsy (AE) is a common type of genetic generalized epilepsy (GGE), particularly in children. AE and GGE are complex genetic diseases with few causal variants identified to date. Gria4 deficient mice provide a model of AE, one for which the common laboratory inbred strain C3H/HeJ (HeJ) har...

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Detalles Bibliográficos
Autores principales:	Frankel, Wayne N., Mahaffey, Connie L., McGarr, Tracy C., Beyer, Barbara J., Letts, Verity A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091709/ https://www.ncbi.nlm.nih.gov/pubmed/25010494 http://dx.doi.org/10.1371/journal.pgen.1004454

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