Inferring Clonal Composition from Multiple Sections of a Breast Cancer

Cancers arise from successive rounds of mutation and selection, generating clonal populations that vary in size, mutational content and drug responsiveness. Ascertaining the clonal composition of a tumor is therefore important both for prognosis and therapy. Mutation counts and frequencies resulting...

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Detalles Bibliográficos
Autores principales: Zare, Habil, Wang, Junfeng, Hu, Alex, Weber, Kris, Smith, Josh, Nickerson, Debbie, Song, ChaoZhong, Witten, Daniela, Blau, C. Anthony, Noble, William Stafford
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091710/
https://www.ncbi.nlm.nih.gov/pubmed/25010360
http://dx.doi.org/10.1371/journal.pcbi.1003703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091710/
https://www.ncbi.nlm.nih.gov/pubmed/25010360
http://dx.doi.org/10.1371/journal.pcbi.1003703

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