Sox11 Is Required to Maintain Proper Levels of Hedgehog Signaling during Vertebrate Ocular Morphogenesis

Ocular coloboma is a sight-threatening malformation caused by failure of the choroid fissure to close during morphogenesis of the eye, and is frequently associated with additional anomalies, including microphthalmia and cataracts. Although Hedgehog signaling is known to play a critical role in choro...

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Detalles Bibliográficos
Autores principales: Pillai-Kastoori, Lakshmi, Wen, Wen, Wilson, Stephen G., Strachan, Erin, Lo-Castro, Adriana, Fichera, Marco, Musumeci, Sebastiano A., Lehmann, Ordan J., Morris, Ann C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091786/
https://www.ncbi.nlm.nih.gov/pubmed/25010521
http://dx.doi.org/10.1371/journal.pgen.1004491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091786/
https://www.ncbi.nlm.nih.gov/pubmed/25010521
http://dx.doi.org/10.1371/journal.pgen.1004491

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