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Dynactin integrity depends upon direct binding of dynamitin to Arp1
Dynactin is a multiprotein complex that works with cytoplasmic dynein and other motors to support a wide range of cell functions. It serves as an adaptor that binds both dynein and cargoes and enhances single-motor processivity. The dynactin subunit dynamitin (also known as p50) is believed to be in...
Autores principales: | Cheong, Frances Ka Yan, Feng, Lijuan, Sarkeshik, Ali, Yates, John R., Schroer, Trina A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091830/ https://www.ncbi.nlm.nih.gov/pubmed/24829381 http://dx.doi.org/10.1091/mbc.E14-03-0842 |
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