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Loss of Somatostatin Receptor Subtype 2 in Prostate Cancer Is Linked to an Aggressive Cancer Phenotype, High Tumor Cell Proliferation and Predicts Early Metastatic and Biochemical Relapse

Somatostatin receptor subtype 2 (SSTR2) is the most frequently expressed SSTR subtype in normal human tissues. SSTR2 expression is differentially regulated in various tumor types and therapeutic somatostatin analogs binding to SSTR2 are in clinical use. In prostate cancers highly contradictory resul...

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Detalles Bibliográficos
Autores principales: Hennigs, Jan K., Müller, Julia, Adam, Matti, Spin, Joshua M., Riedel, Emilia, Graefen, Markus, Bokemeyer, Carsten, Sauter, Guido, Huland, Hartwig, Schlomm, Thorsten, Minner, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091868/
https://www.ncbi.nlm.nih.gov/pubmed/25010045
http://dx.doi.org/10.1371/journal.pone.0100469