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PP2A inhibitors suppress migration and growth of PANC-1 pancreatic cancer cells through inhibition on the Wnt/β-catenin pathway by phosphorylation and degradation of β-catenin

Cantharidin is an active constituent of mylabris, a traditional Chinese medicine, and presents strong anticancer activity in various cell lines. Cantharidin is a potent and selective inhibitor of serine/threonine protein phosphatase 2A (PP2A). Our previous studies revealed the prospect of applicatio...

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Detalles Bibliográficos
Autores principales: WU, MENG-YAO, XIE, XIN, XU, ZE-KUAN, XIE, LI, CHEN, ZHENG, SHOU, LIU-MEI, GONG, FEI-RAN, XIE, YU-FENG, LI, WEI, TAO, MIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091883/
https://www.ncbi.nlm.nih.gov/pubmed/24926961
http://dx.doi.org/10.3892/or.2014.3266