Metformin sensitizes chemotherapy by targeting cancer stem cells and the mTOR pathway in esophageal cancer

Our clinical study indicates esophageal adenocarcinoma patients on metformin had a better treatment response than those without metformin. However, the effects of metformin and the mechanisms of its action in esophageal cancer (EC) are unclear. EC cell lines were used to assess the effects of metfor...

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Detalles Bibliográficos
Autores principales: HONJO, SOICHIRO, AJANI, JAFFER A., SCOTT, AILING W., CHEN, QIONGRONG, SKINNER, HEATH D., STROEHLEIN, JOHN, JOHNSON, RANDY L., SONG, SHUMEI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091970/
https://www.ncbi.nlm.nih.gov/pubmed/24859412
http://dx.doi.org/10.3892/ijo.2014.2450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091970/
https://www.ncbi.nlm.nih.gov/pubmed/24859412
http://dx.doi.org/10.3892/ijo.2014.2450

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