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Metformin sensitizes chemotherapy by targeting cancer stem cells and the mTOR pathway in esophageal cancer
Our clinical study indicates esophageal adenocarcinoma patients on metformin had a better treatment response than those without metformin. However, the effects of metformin and the mechanisms of its action in esophageal cancer (EC) are unclear. EC cell lines were used to assess the effects of metfor...
Autores principales: | HONJO, SOICHIRO, AJANI, JAFFER A., SCOTT, AILING W., CHEN, QIONGRONG, SKINNER, HEATH D., STROEHLEIN, JOHN, JOHNSON, RANDY L., SONG, SHUMEI |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091970/ https://www.ncbi.nlm.nih.gov/pubmed/24859412 http://dx.doi.org/10.3892/ijo.2014.2450 |
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