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Genome-Wide Data reveals Novel Genes for Methotrexate Response in a Large Cohort of Juvenile Idiopathic Arthritis Cases

Clinical response to methotrexate (MTX) treatment for children with juvenile idiopathic arthritis (JIA) displays considerable heterogeneity. Currently, there are no reliable predictors to identify non-responders: earlier identification could lead to targeted treatment. We genotyped 759 JIA cases fro...

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Detalles Bibliográficos
Autores principales: Cobb, Joanna, Cule, Erika, Moncrieffe, Halima, Hinks, Anne, Ursu, Simona, Patrick, Fiona, Kassoumeri, Laura, Flynn, Edward, Bulatović, Maja, Wulffraat, Nico, van Zelst, Bertrand, de Jonge, Robert, Bohm, Marek, Dolezalova, Pavla, Hirani, Shashi, Newman, Stanton, Whitworth, Pamela, Southwood, Taunton R, De Iorio, Maria, Wedderburn, Lucy R, Thomson, Wendy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091986/
https://www.ncbi.nlm.nih.gov/pubmed/24709693
http://dx.doi.org/10.1038/tpj.2014.3