Cargando…
Genome-Wide Data reveals Novel Genes for Methotrexate Response in a Large Cohort of Juvenile Idiopathic Arthritis Cases
Clinical response to methotrexate (MTX) treatment for children with juvenile idiopathic arthritis (JIA) displays considerable heterogeneity. Currently, there are no reliable predictors to identify non-responders: earlier identification could lead to targeted treatment. We genotyped 759 JIA cases fro...
Autores principales: | Cobb, Joanna, Cule, Erika, Moncrieffe, Halima, Hinks, Anne, Ursu, Simona, Patrick, Fiona, Kassoumeri, Laura, Flynn, Edward, Bulatović, Maja, Wulffraat, Nico, van Zelst, Bertrand, de Jonge, Robert, Bohm, Marek, Dolezalova, Pavla, Hirani, Shashi, Newman, Stanton, Whitworth, Pamela, Southwood, Taunton R, De Iorio, Maria, Wedderburn, Lucy R, Thomson, Wendy |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091986/ https://www.ncbi.nlm.nih.gov/pubmed/24709693 http://dx.doi.org/10.1038/tpj.2014.3 |
Ejemplares similares
-
Methotrexate in childhood arthritis: effects on gene expression
por: Moncrieffe, H, et al.
Publicado: (2008) -
Mothers’ reports of the difficulties that their children experience in taking methotrexate for Juvenile Idiopathic Arthritis and how these impact on quality of life
por: Mulligan, Kathleen, et al.
Publicado: (2013) -
Association of the 5-aminoimidazole-4-carboxamide ribonucleotide transformylase gene with response to methotrexate in juvenile idiopathic arthritis
por: Hinks, Anne, et al.
Publicado: (2011) -
Can inflammatory markers predict response to methotrexate in JIA? Results from the CHARM study
por: Moncrieffe, H, et al.
Publicado: (2011) -
Characterising inflammatory markers in two childhood autoimmune diseases (JIA and JDM) pre and post methotrexate
por: Ursu, S, et al.
Publicado: (2011)