Chaperones Ameliorate Beta Cell Dysfunction Associated with Human Islet Amyloid Polypeptide Overexpression

In type 2 diabetes, beta-cell dysfunction is thought to be due to several causes, one being the formation of toxic protein aggregates called islet amyloid, formed by accumulations of misfolded human islet amyloid polypeptide (hIAPP). The process of hIAPP misfolding and aggregation is one of the fact...

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Detalles Bibliográficos
Autores principales: Cadavez, Lisa, Montane, Joel, Alcarraz-Vizán, Gema, Visa, Montse, Vidal-Fàbrega, Laia, Servitja, Joan-Marc, Novials, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092029/
https://www.ncbi.nlm.nih.gov/pubmed/25010593
http://dx.doi.org/10.1371/journal.pone.0101797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092029/
https://www.ncbi.nlm.nih.gov/pubmed/25010593
http://dx.doi.org/10.1371/journal.pone.0101797

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