Investigation of a MMP-2 Activity-Dependent Anchoring Probe for Nuclear Imaging of Cancer

PURPOSE: Since matrix metalloproteinase-2 (MMP-2) is an important marker of tumor malignancy, we developed an original drug design strategy, MMP-2 activity dependent anchoring probes (MDAP), for use in MMP-2 activity imaging, and evaluated the usefulness of this probe in in vitro and in vivo experim...

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Detalles Bibliográficos
Autores principales: Temma, Takashi, Hanaoka, Hirofumi, Yonezawa, Aki, Kondo, Naoya, Sano, Kohei, Sakamoto, Takeharu, Seiki, Motoharu, Ono, Masahiro, Saji, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092090/
https://www.ncbi.nlm.nih.gov/pubmed/25010662
http://dx.doi.org/10.1371/journal.pone.0102180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092090/
https://www.ncbi.nlm.nih.gov/pubmed/25010662
http://dx.doi.org/10.1371/journal.pone.0102180

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