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Forkhead Box L1 Is Frequently Downregulated in Gallbladder Cancer and Inhibits Cell Growth through Apoptosis Induction by Mitochondrial Dysfunction

BACKGROUND: Forkhead box L1 (FOXL1), considered as a novel candidate tumor suppressor, suppresses proliferation and invasion in certain cancers. However, the regulation and function of FOXL1 in gallbladder cancer (GBC) remains unclear. METHODS: FOXL1 expression at mRNA and protein levels in GBC tiss...

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Detalles Bibliográficos
Autores principales: Qin, Yiyu, Gong, Wei, Zhang, Mingdi, Wang, Jiandong, Tang, Zhaohui, Quan, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092092/
https://www.ncbi.nlm.nih.gov/pubmed/25010679
http://dx.doi.org/10.1371/journal.pone.0102084