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Dendritic Cell-Secreted Lipocalin2 Induces CD8(+) T-Cell Apoptosis, Contributes to T-Cell Priming and Leads to a T(H)1 Phenotype
Lipocalin 2 (LCN2), which is highly expressed by dendritic cells (DCs) when treated with dexamethasone (Dex) and lipopolysaccharide (LPS), plays a key role in the defence against bacteria and is also involved in the autocrine apoptosis of T-cells. However, the function of LCN2 when secreted by DCs i...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092100/ https://www.ncbi.nlm.nih.gov/pubmed/25010215 http://dx.doi.org/10.1371/journal.pone.0101881 |