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SOX2 Expression Is Regulated by BRAF and Contributes to Poor Patient Prognosis in Colorectal Cancer

Sporadic colorectal cancer (CRC) is a common malignancy and also one of the main causes of cancer deaths worldwide. Aberrant expression of the transcription factor SOX2 has recently been observed in several cancer types, but its role in CRC has not been fully elucidated. Here we studied the expressi...

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Detalles Bibliográficos
Autores principales: Lundberg, Ida V., Löfgren Burström, Anna, Edin, Sofia, Eklöf, Vincy, Öberg, Åke, Stenling, Roger, Palmqvist, Richard, Wikberg, Maria L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092103/
https://www.ncbi.nlm.nih.gov/pubmed/25010701
http://dx.doi.org/10.1371/journal.pone.0101957